Thursday 24 February 2011

Symptoms, Causes And Treating Of Scleroderma

Symptoms, Causes And Treatment Of Scleroderma

What Is Scleroderma?

Scleroderma is an autoimmune disease that deals particularly with the connective tissues. These connective tissues act like glue between our cells and can be found at almost all parts of our bodies. Since it is an autoimmune disease, it is characterized by having the body’s immune system attack itself instead of protecting it, causing the development of scar tissue and the limiting of the functions of some of the affected organs.

If scleroderma affects more than one area, then that case is known as systemic sclerosis. The more common form of this which would only affect one organ, most commonly the skin is known as morphea. This case, although it could disable a victim would not be fatal most of the time. Systemic sclerosis on the other hand could tend to be fatal.

Who Can Get It?

As of this time, there is still no known cause of scleroderma however, cases have appeared in every gender, age and race although it is more likely to develop in others than it is on some. Scleroderma is four times more likely to appear in women than it is on men and it usually develops somewhere between the ages of 30 to 50. It is also inherent in the Native American Choctaw tribe and in African American women. Scleroderma rarely appears in children.

While there has been no known cause, medical experts have some theories regarding the causes of it. One would be that it is genetic or is a result of heredity or genetic defects. Some would also say that it is environmental, that it is caused by unwanted substances in the environment such as bacteria and viruses. Since the common category for victims of scleroderma would have women that are between the ages 30 and 50, a theory also said that the fetal matter that is left over after pregnancy can cause scleroderma even after years of giving birth. None of these theories however are proven yet.

What Could Happen To A Scleroderma Patient?

Depending on the case, different patients would have different outlooks on scleroderma. Those with limited scleroderma or those who have it on a small area have a considerably good outlook. Most of the time, their case would develop further into another disease other than scleroderma. It is more likely for a case of scleroderma to develop since there is no known treatment for scleroderma.

As for those with systemic scleroderma or those with organ involvement, the outlook is very much negative. Scleroderma is more common in women than it is in men but scleroderma could kill more men. After diagnosis, about two-thirds of all patients would live for at least 11 years. The older the patients are at the time of diagnosis, the more likely their case of scleroderma is to be fatal.

How Is Scleroderma Treated?

Since scleroderma has no known cause, there is also no known cure. Treatment for scleroderma is focused on preventing further damage and relief from discomforting symptoms rather than attempting to entirely remove the disease from the person. A person with organ involvement would take medications or undergo regular therapy in attempt to restore normal activity with these organs.

Scleroderma treatment would also involve having a healthy lifestyle, which means no vices or any unwholesome activities and less stressful activities. Patients of scleroderma would have to take care of themselves more and they should learn to live with their condition.

Saturday 19 February 2011

Sclerosis And The Joints


Sclerosis is when the skin’s surface would suddenly turn into scar tissue or when one would suddenly experience different problems with internal organs that are brought about when an individual’s immune system would start attacking the tissue of that same body. The most visible symptoms of sclerosis is to have some affected areas in the skin however, to know if one is affected, he or she should get diagnosed by a doctor.

Sclerosis is more common in women than it is in men and is rarely found in children. It also happens between the ages of 30 to 60. While sclerosis would affect the skin as well as some organs, it is also notorious for causing a lot of its victims joint pain. Sclerosis could make its victims have dry joints or make the joint movement more limited and in severe cases, it could cripple the victim.

What Causes It?

So far, the cause for sclerosis has never been identified although medical experts have resulted to developing various theories for the cause of sclerosis. Some medical experts would say that sclerosis is very much genetic; having a case of sclerosis in the family would mean that everyone else is at danger of developing it. Some would also say that it is largely environmental and is mainly caused by factors that can be picked up from the environment.

Basing on the common category this would affect which are women in between the ages 30 to 60, some medical experts have thought that the reason behind scleroderma are the fetal remnants left over that are still circulating in the mother’s bloodstream. They say that even after decades after birth, these could still cause scleroderma. This however is yet to be proven and is not backed by sufficient evidence. Even with the main cause of scleroderma being unknown, a lot of cases have still been managed and treated effectively with the use of medications and other methods.

How Does It Affect Joints?

Scleroderma would affect different organs and body parts differently, the only common thing with how it would affect them is that it would cause the patient pain and would limit the activities of the affected area. As for joints, they become less flexible and would cause sharp pain similar to rheumatism or arthritis. This could also lead to the patient being crippled over time if the symptoms do not improve in time.

This is because the antibodies are attacking the bone itself and could also be attacking the nearby muscles depending on the case. If you would get diagnosed with an x-ray, it would show that the bone is whiter than it should be, that of which indicates degeneration in the bone. If that is so, then that degeneration is expected to get worse by the moment until the bone is very brittle and could later start cracking.

How Is It Treated?

With the cause of scleroderma being yet unknown, there is also no single drug that would cure all cases of it. Treatment for scleroderma is specific depending on the case and on the patient as for joint problems, this is usually done first by having it diagnosed with joint x-rays and if it is confirmed that the bones are affected by scleroderma, the patient then will undergo physical therapy for them to be able to manage having limited movement.

Saturday 12 February 2011

Scleroderma In The Kidneys

Scleroderma And The Kidneys

Scleroderma means hard skin when directly translated. It is a disease that would cause the surfaces of your skin and other organs to harden into scar tissue and would usually involve pain and a lot of problems that would involve the affected organs. Scleroderma is most common in women that are between the ages 30 to 60 and rarely happens to children.

At most times, scleroderma would only affect a portion of the skin and is usually visible by tight skin in the face and on the fingers. If it starts affecting the organs, then that is a more sever case known as systemic sclerosis. This may affect the lungs, heart, intestines and the kidney. If the kidney is affected by sclerosis, this would limit the kidney’s functions and as well could cause some pain to the patient. It could however be managed and dealt with medical approaches to scleroderma kidney involvement.

What Causes Scleroderma?

As of today, there is still no known cause for scleroderma. Medical experts however have developed numerous theories in attempt of knowing what the causes are. Some would say that it is largely genetic and that a patient of scleroderma would indicate that his or her relatives are also at danger of developing it. Another would say that it is largely environmental and that it is caused by factors that are influenced by the environment surrounding the patient.

A medical expert also theorized with the common category being women aged 30 to 60 as a basis that the fetal remnants left over that are still circulating in the bloodstream can cause sclerosis even after decades after giving birth. None of these theories however have been proven and as of now, the cause of sclerosis still remains unknown and is yet to be found.

How Does Scleroderma Affect The Kidneys?

While scleroderma would occur in the skin in around 95% of all cases, having it develop in the kidneys is also quite common for those who have it. Scleroderma mainly affects the blood vessels that are in the kidneys this of which is known as scleroderma renal crisis. This would lead to a sudden rise in blood pressure of the patient as well as a rapid decline in renal function that would happen over days. This may lead to complete renal failure that in turn can cause death.

Before, the leading cause of death for scleroderma victims was renal crisis. Fortunately, drugs of which are known as Angiotension Converting Enzyme Inhibitors or ACE inhibitors have lessened this number significantly and if that does not work, there are still other medications that would serve the purpose effectively. ACE inhibitors are also used commonly to treat high-blood pressure.

How Are Cases Concerning Kidneys Treated?

While scleroderma has no known cause, it also has no known cure. To relieve a patient from it, treatment for scleroderma would vary depending on the cases and on the individual. For cases concerning the kidneys, it focuses more on blood pressure control with the use of ACE inhibitors. As for people who develop side effects from it, they can use angiotensin receptor blockers. These are so effective and are known to have relieved a lot of patients from cases concerning kidneys.

These medicines however are only made to alleviate a patient from symptoms with the kidneys and are not made to completely relieve a patient from scleroderma.

Friday 11 February 2011

Scleroderma In The Digestive System


Scleroderma is characterized by the toughening of the affected area, most commonly in the skin or in the organs which could lead to limitation of the organ’s function. This is quite rare as it only affects 14 out of every 1 million people worldwide. Scleroderma affects women more than it affects men and could develop somewhere between the ages of 30 to 50. It is also inherent in the Native American Choctaw tribe and in African-American women. Scleroderma is rarely found in children.

While cases of scleroderma that would only affect the skin would most likely not be fatal but could cripple the patient, the severe form of it which is called systemic scleroderma or is characterized by having scleroderma affect various parts of the body can be lethal and has been proven so in many cases. After the skin which is the most common case which would account for 95% to 100% of all cases, it is followed by gastro-intestinal involvement in scleroderma which would account for 70% to 90%

How Is The Digestive System Involved In Scleroderma?

Scleroderma is an autoimmune disease. Being that, it mainly interferes with the immune system and having them attack the body instead of protecting it. Scleroderma can affect all organs of the digestive system, either just one organ or the entire system at the same time. It start with the esophagus; if scleroderma is present in the esophagus, then peristalsis is more difficult as the food track is tighter making it less able to push food down.

Gastro-intestinal involvement in scleroderma usually starts off with the esophagus and gradually makes its way down lower into the large intestine. If it makes its way past the stomach, then the patient will start having problems with digesting food. This is because the stomach now lacks blood vessels because it has been limited by scleroderma. Worst case scenario of this is that everything from the esophagus to the rectum would be affected. Unfortunately, this is very possible.

How Is This Treated?

As of today, there is no known cause for scleroderma and because of that, diagnosis is mainly based on symptoms. Doctors can start off by giving a patient medication to help ease him or her of the symptoms. These medications are given in attempt to lessen acid production but if that does not do anything, then procedures that are specific to the affected area are done to relieve a patient of discomforting symptoms.

Medications however are only given to relieve a patient from the effects brought about by scleroderma and not to entirely remove scleroderma from a patient. The cause of scleroderma is unknown and with that, there is no known medicine. Treatment for scleroderma is patient-specific even when it comes to gastro-intestinal involvement. This however can be managed effectively with the help of medical procedures.

How Is This Diagnosed?

If medications do not work or if a patient would develop side effects, then that is where one should have medical procedures. If the esophagus is affected, some medical procedures that can help would be endoscopy, barium swallow and esophageal manometry.

If the stomach is affected, then the patient could also have barium swallow which is similar the one referring to esophageal involvement and a gastric emptying study of which a person eats small amounts of material followed by taking x-rays of their stomach.

Tuesday 8 February 2011

Scleroderma and Renal Problems

Scleroderma and Renal Crisis

Scleroderma renal crisis is the term used to describe kidney involvement in scleroderma because of the very much discomforting symptoms brought about by it that indeed puts the patient into a crisis. This happens when scleroderma, of which the cause is unknown, would reach the kidneys, limiting blood supply to it and limiting its functions or totally impairing it. This condition could only happen to those with the diffuse form of scleroderma which is called limited sclerosis.

Kidney involvement in scleroderma would usually start of as an increase in blood pressure then would later show more signs within weeks or days. Scleroderma renal crisis is mainly associated with a decrease in kidney function, the appearance of protein in urine and in severe cases, accompanied by heart failure.

How Does This Develop?

Scleroderma would usually start of in the skin in the form of calcinosis or Raynaud’s phenomenon. If it sticks with those symptoms, then that case of scleroderma is most likely limited scleroderma or CREST which is the milder form of the illness. Although this can disable, it would tend most of the time not to be fatal. However, if it spreads to the internal organs, the kidneys in particular, then that would be the beginning of scleroderma renal involvement.

The connective tissues in the kidneys are the ones that are primarily involved in scleroderma. Scleroderma causes scar tissue to develop in them, thus making them thicker. This also limits blood flow to the kidneys that in turn could impair or actually kill some parts of the kidney or the kidney itself. This could also lead to heart complications that in sever cases, could lead to heart failure.

Start Treatment Early

Patients with renal involvement in scleroderma should start treatment as early as possible. This condition is quite serious and could develop before anyone would know. To prevent further damage, it is highly advisable that a patient should start treatment early. If ever there would be significant damage done to the kidneys, little can be done to reverse the effects.

The effectiveness of treating renal involvement in scleroderma would depend heavily on the level of damage already inflicted at that time of treatment. The less damage there is, the more likely a patient would recover from the condition. Since scleroderma in general has no known cure, treatment for renal involvement is more focused on limiting damage.

Can This Condition Be Treated?

Even if scleroderma in general has no treatment, a lot of things can still be done to help relieve a patient from the damages done by scleroderma to the kidneys. However if the kidney is already totally impaired, little can be done to reverse the effect. But if treatment would start early, then treatment is very possible through medical help which would involve medications, rehabilitation therapies and surgery for some cases.

The point that all patients or those who are widely involved with renal scleroderma is that it is treatable and a lot has been done in the past to help cure people with this condition. The key to relief from it is early treatment as well as taking medications religiously and as well as careful medical attention.

Because renal involvement in scleroderma is quite sensitive, this would require the utmost attention of the doctor as well as a lot of effort from the patient.

Friday 4 February 2011

Scleroderma And Elbow Pain

Scleroderma And Elbow Pains

Background

Scleroderma is an autoimmune disease that is characterized by having the antibodies attack their own tissues, which is contrary to their main purpose of protecting it. That in turn would cause the affected area to thicken and its functions to be limited. The more common form of scleroderma which is limited scleroderma or CREST would tend not to be fatal, although it can cripple a patient. The severe from of it which it systemic scleroderma is the more fatal type.

Scleroderma is quite rare as it only affects 14 out of every 1 million people worldwide. Scleroderma affects women more than it affects men and is usually develops within the ages 30 and 50. This illness is inherent in African-American women and the Native American Choctaw tribe. It rarely occurs in northern Asians and in children.

What Are The Causes Of Scleroderma?

As of now, there is no accurate cause of scleroderma although medical experts suspect some factors to cause it. One of those factors is genetics; they say that scleroderma is in the genes and those with genetic defects are more susceptible to the disease. Another is an unhealthy environment that could expose a patient to some factors that may cause it such as bacteria, viruses and similar factors. Hormones could also play a role as to why it happens to more women than it does on men.

Another theory made by medical experts is that the fetal matter that is left over after pregnancy that is still circulating in the mother’s system can cause scleroderma even after years of giving birth. This is why the most common category for patients with scleroderma are women between ages 30 and 50. While these theories may be reasonable and logical, none of these are proven yet and they still remain as theories.

How Does Scleroderma Develop In The Elbows?

Scleroderma can occur in most parts of the body such as the skin, the lungs, kidneys, stomach, esophagus, intestines, heart and the bones however, the elbows are some of the most affected parts when it comes to scleroderma involvement. The thickening of the tissues in the elbow will bring about limitations in its movement and as well as can be accompanied by pain. The cause of this, which are most likely calcium deposits can actually be seen and felt.

The elbows are quite sensitive and can be affected even in limited scleroderma, especially the tips of the elbows called the olecranon area. If a patient’s elbows are affected by scleroderma, this can lead to discomforting irritation and tenderness if pressure is applied on the elbows. Fortunately, this is very possible to be treated.

How Can This Be Treated?

There is no known treatment for all cases of scleroderma. The approach for treating scleroderma is patient-specific and is more focused on preventing further damage and on treating individual symptoms. As for cases with elbow involvement, this can be treated with tropical lubricants and emollients. But if ever the patient would develop side effects or if these medications would not work at all, the patient can avail of alternative medicine.

One of the known alternative medicines that have proven effective in treating this condition is Bagbalm, this of which you would only apply to the tender areas of the affected area. Bagbalm is available over the counter and does not require any medical prescription.